5. 1889 Flu Pandemic
Thought to be the first true epidemic in the era of bacteriology the “Asiatic Flu” or “Russian Flu” spread across the globe. The first cases were observed in May 1889 in three separate and distant locations, Bukhara in Central Asia (Turkestan), Athabasca in northwestern Canada, and Greenland.
This strain was thought to be an outbreak of the Influenza A virus subtype H2N2, though recent discoveries have instead found the cause to be the Influenza A virus subtype H3N8. With the help of a population boom in urban areas between 1889 and 1890, this pandemic would take the lives of a million people over the course of a single year.
6. The Sixth Cholera Pandemic
Like it’s previous incarnations, the sixth cholera outbreak between 1910 to 1911 originated from India spreading from the Ganges River Delta before this time making its way across the Middle East, North Africa, Eastern Europe and Russia, claiming the lives of over 800,000 people.
However, when it arrived in the United States the American health authorities had learned from previous outbreaks, so were quick to isolate the infected. In the end, only 11 deaths were attributed to the cholera outbreak.